What Are The Causes Of FSGS

The causes of FSG are largely unknown. In such cases it is called idiopathic or primary FSGS. But, FSGS does have some known cause.

What are the causes of FSGS?

The main causes of FSGS include two aspects: internal kidney reason and the external kidney reason. When the glomerular epithelial cells are injured due to massive immune complexes deposition. In case of abnormal immune system, people will easily get infections, colds, etc. Then antigens (bacteria, virus) will enter into the body and then combine with antibody, producing immune complex.

The special epitopes in the kidneys can attract the immune complexes, so the immune complexes will flow with blood circulation and deposit in the glomerular capillary loops, which gives rise to segmental hyaline degeneration in the epithelial cells of the glomerulus. As a result, the surface of epithelial cells of the glomerulus is desquamation, and inflammatory mediator continues to invade, leading to the damages of epithelial cells barrier function.

The segmental sclerosis of glomeruli reflects the result of damage reparation of local inflammation. Primary FSGS is often accompanied by the harms of glomrular epithelial cells. The epithelial cells of visceral layer, or you can call it podocyte, plays an important function in the onset of the primary FSGS.

Epithelial cells can produce various kinds of cell factor and growth factor. The increase of synthesis of collagen from epithelial and mesangial cells and also lead to the decrease of degradation, therefore leading to the glomerular sclerosis.

Besides, the high filtration and high perfusion also play an important function in the formation of FSGS.

Other causes

The abnormal length of the ureter that extends into the bladder.

the hereditary forms of FSGS

Reflux nephropathy, in which urine flows back into the kidney.

Secondary to viral infections such as HIV, parvovirus, and hepatitis B.

Glomerulonephritis, which causes the glomeruli to become inflamed.

Heroin or other drug use.

Birth defects of the kidneys.

If you want to know more information about FSGS causes and treatment, you can leave a message below or you can email us igancure@hotmail.com.

Maintenance To Help Prevent Kidney Disease

A proper maintenance can help prevent the onset of kidney disorders. You can do this by:

Diet and exercise: Making heart-healthy food choices and exercising regularly to maintain a healthy weight can help prevent the diseases that cause further kidney damage.

Blood Pressure: If you have high blood pressure, make sure that you keep a control blood pressure. High blood pressure can damage your kidneys and can cause chronic kidney failure.

Salt: Choose and prepare foods with less salt and sodium. Aim for less than 1,500 milligrams of sodium each day.

Cholesterol: Too much cholesterol can build up in your blood vessels. This build up can narrow vessels and lead to a blockage, preventing blood from getting to a certain areas of your body. When this occurs in your heart vessels, it is called coronary heart disease and can cause a heart attack.

Diabetes: If you have diabetes, you can keep kidney disease from forming by monitoring your blood sugar levels. You can do this by proper dieting and staying away from sugary foods.

Weight: A proper weight can help prevent other disease from forming such as high blood pressure, and heart disease.

Protein: Eat the right amount of protein. Although it is important to eat enough protein to stay healthy, excess protein makes your kidneys work harder. Eating less protein may help delay progression to kidney failure.

Smoking: Stay away from smoking because smoking can lead to atherosclerosis. Which can reduce blood flow to the kidneys and can increase your blood pressure. So, take steps to quit. Cigarette smoking can make kidney damage worse.

Eating healthy is the key from keeping  your blood vessels from forming blockage and heart disease. If you do these things, you can help keep diseases away from you. If you have been diagnosed with kidney disease, ask your doctor about seeing a dietitian. A dietitian can teach you how to choose foods that are easier on your kidneys.

If you want to learn more knowledge about kidney disease, please email to igancure@hotmail.com. I'm glad to help you.

Causes of IgA Nephropathy

IgA Nephropathy brings kinds of troubles in normal life, and it can cause blood and protein in the urine, high blood pressure and edema. Many patients with IgA Nephropathy are confused about the causes of this antoimmune disorder.

The following are the causes of IgA Nephropathy:

1. Infection and Inflammatory reaction
Infection will cause inflammatory reaction inside the body which affects mesangial cells, resulting in secretion of inflammatory cytokines. Finally, massive immune complexes accumulate in the mesangial area of kidney. IgA has strong affinity with glomerular mesangial cells and the combination of them will lead to the phenotype transformation of renal inherent cells and cause IgA Nephropathy.

2. Genetic predisposition
According to the investigation on IgA Nephropathy patients, a part of them show familial aggregation, which means that IgA Nephropathy has hereditary tendency in some degree.

3. Bone morrow disorders
The IgA depositing in the kidneys is bone marrow-derived.

4. Abnormal cellular inflammatory factors
The IgA1 in the mesangial areas will cause the mesangial cells to secrete inflammatory factors and cause extreme inflammatory reaction resulting in damages of renal structure and renal function.

For more information about IgA Nephropathy, you can leave us a message below or you can email us to igancure@hotmail.com.

What are the treatments for FSGS?

FSGS is not an easy condition to treatment, but many treatments can be applied to stop FSGS effectively.

1. Conventional Treatments for FSGS

Hormone and cytotoxicity drugs are the currently common used drugs for the treatment of FSGS.

As for the relapse FSGS after kidney transplant, the effect of blood purification treatment is relatively satisfactory.

2. Dialysis and Kidney Transplantation

Generally, dialysis and kidney transplantation are adopted when FSGS develops to kidney failure. However, dialysis is just like a filter machine, it only can help the patient to discharge the waste products from human body.

3. Chinese Medicine Acupoint Injection

Chinese Medicine Acupoint Injection is a kind of treatment method of injecting the special- made herbal medicine into the acupoint and through the acupoint running to the lesion to hasten the medicine absorbed . This method is giving the medicine to some local acupoint related the kidney channel to stimulate the organic nonspecific immune reaction, to achieve adjusting body’s internal environment, to reduce the body’s sensibility and enhance its immunity, to restrain the inflammatory reaction inside of the body, to improve disease resistance and promote the repairing the lesion of renal tissues.

4. Immunotherapy
Immunotherapy can help patients regulate the immune system, through a series of immune blocking methods, we can restrain the immune reaction rapidly so as to prevent further damages to renal tissues and intrinsic cells.

5. Dietary therapy
Dietary therapy is through limit the intake of fluid, fat, protein, etc.

6. Other
For example, Chinese Herbal Medicines, Natural therapy, etc.

If you want to learn more knowledge about kidney disease, please email to igancure@hotmail.com.  I'm glad to help you.

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These two videos are dialysis patients and bid farewell to Somalia,if you are interested in this therapy, please visit www.igancure.com

Diet For FSGS

Diet plays a huge role in prevention of FSGS and relieving the illness condition in sufferers. But many patients still do not know what foods they can eat with FSGS. In that condition, what on earth can FSGS patients eat?

Here are some dietary tips for FSGS patients to eat.

1. Low-salt diet
As FSGS patients are likely to suffer hypertension and swelling, so they should restrain water and sodium intake. No eating salty food, drinking, pickles, such things like that. Limit sodium intake carefully.

2. Protein intake.
Protein is an essential substance for human body, in particular, FSGS patients. Damaged kidneys fail to bear heavy burden, so to avoid extra kidney burden. Besides, FSGS patients should absorb some high quality protein foods which can be found in lean meat, fish, egg white and milk.

3. Control potassium intake
Low-potassium diet helps FSGS patients to prevent heart problem. Therefore, controlling potassium intake will decrease the risk of dying of heart failure.

4. Eat low phosphorus foods
High levels of phosphorus restrains calcium intake, which can cause bone diseases. Therefore, if lab tests show FSGS patients have elevated phosphorus level, foods with low phosphorus will be suggested.

5. Make sure ingest enough vitamin
Because of serious diet limitation, many FSGS patients can not get enough vitamin from vegetables and fruits. In serious case, they can eat some vitamin supplements to make sure enough vitamin in their body.

The above are some general dietary tips for you and do not suit for specific individual. Therefore, if you want to know what diet suits you, you can email to igancure@hotmail.com

2014 The Newest Therapy For Kidney Disease

The kidneys are two organs located on either side of your spine in the middle of your back, above the waist. When the kidneys become damaged, causing swelling in your ankles,weakness, poor sleep,  vomiting, and shortness of breath. If left untreated, diseased kidneys may eventually stop functioning completely. Recently, the emergence of newest therapy for kidney disease. It bring a promising future for kidney disease patients. It's Cycle Therapy. Then, what are Cycle Therapy?

Cycle Therapy are crushing the Chinese medicines that smearing them on different body parts according to various kidney diseases, and drawing out toxins from blood tier with different medicines.  All of these medicines, but you need not worry any side effects because all the medicines come from the nature and be fully micronized.

Cycle Therapy have some functions, like anti-inflammation, expanding blood vessels, removing stasis, anti-coagulation, promoting DNA self-replication and providing nutritions to kidneys, etc thus to repair the damaged kidney and improve kidney function from the root. It acts directly on the renal lesions through the skin of the back. In the process, patients will not feel pain. It is a safe treatment

The above are a little introduction, if you want to learn more knowledge about Cycle Therapy, please email to igancure@hotmail.com.  I'm glad to help you.